简介：

赵璐，女，副教授，硕士生导师。研究方向：功能纳米材料、生物传感器、生化分析。近年来，获得山西省高等学校科学技术奖二等奖1项，主持省级科研项目1项，大同市科研项目1项，参与国家自然科学基金、省自然科学基金等项目10余项。参与省级教研项目1项，校级教研项目2项。发表学术论文50余篇，其中被SCI收录40余篇。申请国家发明专利12项，已获授权国家发明专利5项、实用新型专利3项。

教育背景：

2000.09—2004.06  中国矿业大学化工学院应用化学理学学士

2006.09—2008.06  北京交通大学理学院应用化学工学硕士

工作简历：

2008.9—2011.12    山西大同大学化学与化工学院助教

2011.12—2024.12   山西大同大学化学与化工学院讲师

2024.12—至今山西大同大学化学与化工学院副教授

代表性论文：

[1] Lu Zhao,Jianfeng Li,XuehuiZhang,Yunfeng Bai*,Feng Feng*. Cascade Nanoreactor Based on Mo2C MXenefor NIR-II-ActivatedMultimodal Therapy of Cancer. Molecular Pharmaceutics, 2026, 23(3), 1955-1968SCI二区

[2] Lu Zhao, WenliFeng, ChenxiaHao, Lin Yuan, Lizhenliu, Xiaoming Yang*, Yunfeng Bai*, Feng Feng*. Activating aqueous room temperature phosphorescence in N, S, B co-doped carbon dots for Fe3+detection and anti-counterfeiting. SpectrochimicaActa Part A: Molecular and Biomolecular Spectroscopy, 2026, 348, 127243  SCI二区

[3] Hui Xu,Lu Zhao*,XiaoliangChen,Aiai Wang,Jianfeng Li,Yunfeng Bai*,Feng Feng*. Aptamer-Functionalized AuNRNanoplatform for Active TargetedChemo-Photothermal Therapy of Tumor. Bioconjugate Chemistry, 2026, 37(2), 384-394  SCI二区

[4] Lu Zhao, Aiai Wang, Yaru Li, Yunfeng Bai*, Feng Feng*. A smart Zr/Co porphyrin MOFs-based nanotheranostics: Triggering ROS storm for potentiated tumor therapy. Chemical Engineering Journal, 2025, 520, 165992SCI一区TOP期刊

[5] HaizhenLv, Zhiqiang Bai, Yanjun Li*, Lu Zhao*, Yunfeng Bai*,Feng Feng*. Enhanced therapeutic efficacy of folic acid-decorated Ti3C2MXenesin targeted combination therapy for liver cancer. Materials Chemistry Frontiers, 2025, 9(22), 3323-3331SCI三区

[6] Hui Xu, Lu Zhao*, XiaoliangChen, Zhiqiang Bai, Yanjun Li, NianpingZhang, Yunfeng Bai*, Feng Feng*. PD-L1 aptamer-functionalized gold nanorods for targeted combined chemo-photothermal therapy in breast cancer. Bioconjugate Chemistry, 2025, 36(8), 1854-1864SCI二区

[7] Zhiqiang Bai, Lu Zhao*, Zhihui Xin, Jiang Li, Yunfeng Bai*, Feng Feng*. Smart therapeutic nanoplatform based on Ti3C2MXenesfor tumor targeted PTT/PDT/CHT at low temperatures. Molecular Pharmaceutics, 2025, 22(8), 4995-5006  SCI二区

[8] Jianfeng Li, Zhihui Xin, Zhiqiang Bai, Jiang Li, Lu Zhao*,Yunfeng Bai*, Feng Feng*. A smart nanocomposite based on Mo2C MXenefor active targeted photothermal-chemotherapy of cancer in NIR-II biowindows. ACS Biomaterials Science & Engineering, 2025, 11(6), 3307-3317  SCI三区

[9] WenliFeng, Lu Zhao*, ChenxiaHao, Lin Yuan, LizhenLiu, Xiaoming Yang*, Yunfeng Bai*, Feng Feng*. Ultra-stable room temperature phosphorescence CDs-based composite materials for anti-counterfeiting application. SpectrochimicaActa Part A: Molecular and Biomolecular Spectroscopy, 2025, 337, 126106  SCI二区

[10] Zhihui Xin, Lu Zhao*, Jianfeng Li, Zhiqiang Bai, Yunfeng Bai*, Feng Feng*. Multifunctional nanozyme for tumor-targeted photothermal/catalytic combination therapy. Materials Chemistry Frontiers, 2025, 9(11), 1702-1715  SCI二区

[11] Zhihui Xin, Lu Zhao*, Zhiqiang Bai, ChaoyuWang, ZhixiongLiu, Jun Qin, LizhenLiu, Haifei Zhang, Yunfeng Bai*, Feng Feng*. Aptamer-functionalized hollow carbon nanospheres for targeted chemo-photothermal therapy of breast tumor.Materials Chemistry Frontiers, 2024, 8(24), 4049-4058  SCI二区

[12] MeiqingLiu, Lu Zhao*, Yuying Chen, XiaoliangChen, Jiang Li, ZezhongChen, Hui Xu, Yingying Zhao, Yunfeng Bai*, Feng Feng*. Aptamer-modified Nb2C multifunctional nanomedicine for targeted photothermal/chemotherapy combined therapy of tumor. Molecular Pharmaceutics, 2024, 21(8), 4047-4059   SCI二区

[13] ChaoyuWang, Zhihui Xin, Zhiqiang Bai, Jiaxin Mao, Yaru Li, ZhifangJia, KeweiWang, LuZhao*, Yunfeng Bai*, Feng Feng*. A Covalent Organic Frameworks-based Nanoplatform with Enhanced Photothermal and Photodynamic Performance for Targeted Tumor Therapy. Materials Chemistry Frontiers, 2024, 8(16), 2736-2744   SCI二区

[14] 赵璐，王涛，王超宇，毛佳欣，刘志雄，李雅茹，白云峰*，冯锋*．基于杂交链式反应和共价有机框架的新型荧光传感器用于ctDNA的高灵敏和选择性检测（英文），化学通报，2024，87(4)，456-463   中文核心

[15] Lu Zhao, Jie Liu, Yunfeng Bai, YaqiongWen*, Xiaoming Yang*. Exploration of nisin-directed gold nanoclusters employed for detecting thiourea and the sensing mechanism. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022, 652, 129847  SCI二区

[16] Lu Zhao, Yunfeng Bai, YaqiongWen*, Xiaoming Yang*. Orange-fluorescence carbon dots employed for the quantitative analysis of silver ions and glyphosinethrough the off–on mode. Analytical Methods, 2022, 14(42), 4230-4235  SCI三区

[17] Lu Zhao, Zheng-Fei Liu, Wei Jun Jin*, Feng Feng*. Luminescence property of phosphoramidicacid oligomer nanodots in aqueous solution. SpectrochimicaActa Part A: Molecular and Biomolecular Spectroscopy, 2021, 248, 119261   SCI二区

[18] Lu Zhao, Jie Liu, Yunfeng Bai, Feng Feng*, Xiaoming Yang*. Exploration of carbon dots derived from epimedium towards detecting dopamine and hydrogen peroxide. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2021, 627, 127179   SCI二区

[19] Lu Zhao, Jie Liu, Yunfeng Bai, Feng Feng*, Xiaoming Yang*. Yellow-emission and pH-responsive carbon dots employed for “turn-off” and “turn-off-on” assaying adenosine triphosphate and kanamycin. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2021, 630, 127640   SCI二区

课题研究：

[1] 基于MXenes的复合纳米载药系统对肿瘤靶向治疗的研究（2022L424），山西省高等学校科技创新项目，2022.09—2024.09

[2] 基于空心碳纳米球的复合载药系统用于肿瘤靶向治疗的研究（2022K18），山西大同大学基础科研基金项目，2023.3—2025.3

[3] 基于适体修饰Cu-MOFs的纳米治疗系统对肿瘤靶向治疗的研究（2023065），大同市应用基础研究项目，2023.12—2026.12

[4] 碳基肿瘤靶向纳米药物的研发，北京贵运通科技有限公司，横向项目，2024.11—2027.11

获奖：

[1] 基于功能核酸的光化学生物传感器研究，山西省高等学校优秀成果奖（科学技术），自然科学奖二等奖，2020.6

国家发明专利：

[1] 一种Fe/Mn 卟啉基双金属有机骨架及其制备方法和应用．国家发明专利，申请日期：2025.7.14. 申请号：CN202510967127.9

[2] 一种具有双酶活性的复合纳米材料及其制备方法和应用．国家发明专利，申请日期：2025.6.13. 申请号：CN202510793491.8

[3] 一种多功能肿瘤靶向低温治疗纳米平台及其应用．国家发明专利，授权日期：2025.11.11，专利号：ZL202510117488.4

[4] 一种多功能纳米酶及其制备方法和应用．国家发明专利，申请日期：2024.11.8. 申请号：CN202411592970.5

用于乳腺癌治疗的主动靶向纳米药物及其制备方法和应用．国家发明专利，申请日期：2024.4.26. 申请号：CN2024105148070

[5] 一种乳腺癌靶向纳米药物及其制备方法和应用．国家发明专利，申请日期：2024.4.22. 申请号：CN2024104853191

[6] 用于乳腺癌联合治疗的靶向纳米药物及其制备方法和应用．国家发明专利，申请日期：2024.4.22. 申请号：CN2024104853223

[7] 一种纳米靶向载药复合物及其制备方法和应用．国家发明专利，授权日期：2026.2.13，专利号：ZL202211049693.4

[8] 一种二氧化硅/氮掺杂碳纳米复合物及其制备方法与应用．国家发明专利，授权日期：2024.6.7，专利号：ZL202110812737.3

[9] 基于杂交链式反应和核酶的荧光适配体传感器及其应用．国家发明专利，申请日期：2020.11.5，申请号：CN202011225724.8

[10] 基于杂交链式反应和核酶的传感器及癌胚抗原检测方法．国家发明专利，授权日期：2023.10.27，专利号：ZL202010080734.0

[11] 基于杂交链式反应的荧光DNA传感器及E542K基因检测方法．国家发明专利，授权日期：2022.9.9，专利号：ZL202010080730.2